Every 15 seconds, someone in the US suffers a traumatic brain injury


About BBT

Beyond Barriers Therapeutics, Inc. is developing a novel product to treat inflammation and cell death following traumatic brain injury (TBI). Building upon promising research from the National Institutes of Health, our product uses a unique mechanism to deliver therapeutic drugs to the brain.

Every 15 seconds, an American suffers a traumatic brain injury (TBI), hospitalizing 230,000 people annually at a cost of more than $50 billion. Because of a lack of specific therapies for TBI, people are mainly treated with a "wait and see" approach. Our veterans, children, and elderly deserve more.

We are developing a treatment that could be administered intranasally immediately after impact to the head, which would help prevent secondary injury to the brain. In the hours and days following initial injury, toxic molecules and dangerous inflammation can occur in the brain, contributing to debilitating long-term disabilities for patients. Our treatment aims to decrease these harmful effects by providing active therapy.


In addition to significantly improving standard of care for patients suffering from TBI, our proprietary technology will lay the foundation for use of a novel, more effective delivery mechanism of small molecules to the brain. After successful testing, this technology could be used to treat a number of other neurological conditions (such as Depression or Alzheimer’s Disease)--generating value throughout the healthcare system.

Meet the Team

Ryan Kole, MBA


Partner at VCapital Management Company


Director of the Midwest Venture Capital Consortium


University of Illinois, BA

University of Chicago, MBA

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John Marshall, PhD

Chief Scientific Officer


Columbia University, BA

Northwestern University, PhD neuroscience

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Tom De Gregoris, JD, MBA

Chief Business Officer/Legal

Corporate & Securities associate at Mayer Brown

Notre Dame, BBA

Northwestern University, JD/MB

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For any questions you have, please contact us.

Beyond Barriers Therapeutics, Inc.

Chicago, IL

© 2020